Case of Successful Sympathetic Nerve Modulation by Targeted Heavy Ion Radiotherapy for Idiopathic Ventricular Tachycardia

ABSTRACT Non‐invasive radioablation using stereotactic body radiation therapy with X‐ray has been proposed as a rescue treatment for refractory ventricular tachycardia (VT). However, there are concerns about the occurrence of late valvular or coronary disease. We treated VT originating from the aort...

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Veröffentlicht in:	Annals of noninvasive electrocardiology 2024-11, Vol.29 (6), p.e70020-n/a
Hauptverfasser:	Amino, Mari, Wakatsuki, Masaru, Mori, Shinichiro, Shimokawa, Takashi, Kabuki, Shigeto, Kunieda, Etsuo, Hashimoto, Jun, Yamashita, Takashi, Yagishita, Atsuhiko, Ikari, Yuji, Yoshioka, Koichiro, Lee, Kyong Hee, Sakama, Susumu, Owaki, Ami, Takahashi, Akari, Shirasu, Misako, Kojima, Yu, Hiroki, Tomoyuki, Todaka, Hideharu, Kuroki, Toshihisa, Fukuzawa, Tsuyoshi, Sugahara, Akitomo, Yamaguchi, Tsubasa, Suzuki, Masatomo, Fujiwara, Yukiko, Yamaguchi, Keiko, Fukushi, Hiromichi, Morita, Seiji, Nakagawa, Yoshihide, Fujii, Takanao, Fujishima, Miho, Motomura, Mari, Shinoto, Makoto, Hasegawa, Sumitaka, Ishikawa, Hitoshi, Yamada, Shigeru, Suzuki, Kazuko, Tsuyuki, Kyoko, Nishimura, Yuka, Shirai, Toshiyuki, Uchihori, Yukio, Hirano, Toshio, Koyasu, Shigeo, Furusawa, Yoshiya
Format:	Artikel
Sprache:	eng
Schlagworte:	123I‐metaiodobenzylguanidine scintigraphy 3-Iodobenzylguanidine - therapeutic use Ablation Aorta Aortic valve arrhythmia radioablation Bragg curve Calcification Carbon Cardiac arrhythmia Cardiomyopathy Case Report Catheters Coronary artery disease Coronary vessels Denervation Drug dosages Electrocardiography Electrocardiography - methods Heart attacks Heart valves Heavy ion radiation Heavy Ion Radiotherapy - methods Heavy ions Heterogeneity Humans Ion beams Ischemia Male Middle Aged Nerves non‐invasive irradiation technique Optimization techniques Pulmonary arteries Radiation Radiation therapy Scintigraphy Sinuses sympathetic denervation Sympathetic nerves Sympathetic Nervous System - physiopathology Tachycardia Tachycardia, Ventricular - physiopathology targeted heavy ion radiotherapy Treatment Outcome Veins & arteries Ventricle ventricular arrhythmia X-rays
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Zusammenfassung:	ABSTRACT Non‐invasive radioablation using stereotactic body radiation therapy with X‐ray has been proposed as a rescue treatment for refractory ventricular tachycardia (VT). However, there are concerns about the occurrence of late valvular or coronary disease. We treated VT originating from the aortic sinus cusp using the Bragg peak principle of a heavy ion beam, minimizing the dose to the aortic valve and coronary artery and providing an anti‐arrhythmic effect and cardiac function recovery due to improved sympathetic nerve heterogeneity. We present a method for targeting sympathetic nerve distribution using 123I‐metaiodobenzylguanidine scintigraphy.
ISSN:	1082-720X 1542-474X 1542-474X
DOI:	10.1111/anec.70020