Right coronary artery diastolic perfusion pressure on outcome of patients with left heart failure and pulmonary hypertension

Aims Right ventricle adaptation to prolonged exposure against pulmonary hypertension (PH) includes structural and functional abnormalities, translated into modifications of blood flow pattern through the right coronary artery. Given these changes, we investigate the relationship between right corona...

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Veröffentlicht in:ESC Heart Failure 2021-10, Vol.8 (5), p.4086-4092
Hauptverfasser: Hamud, Amir, Brezins, Marc, Shturman, Alexander, Abramovich, Adrian, Dragu, Robert
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Sprache:eng
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Zusammenfassung:Aims Right ventricle adaptation to prolonged exposure against pulmonary hypertension (PH) includes structural and functional abnormalities, translated into modifications of blood flow pattern through the right coronary artery. Given these changes, we investigate the relationship between right coronary artery diastolic perfusion pressure (RCDPP) and clinical outcome, in patients with PH secondary to left‐sided heart failure (HF). Methods and results We studied 108 HF patients who underwent right heart catheterization. PH was present in 75 (69.4%). Mean RCDPP was lower in patients with PH (59.4 ± 14.0 mmHg) as compared with no PH patients (65.5 ± 11.6 mmHg) (P = 0.03). Aortic diastolic pressure accounted for 79% of RCDPP variability explained by the model (P 
ISSN:2055-5822
2055-5822
DOI:10.1002/ehf2.13469