Apoptosis-Inducing Action of Antituberculosis Drugs of the Main Group in Vitro

Apoptosis-Inducing Action of Antituberculosis Drugs of the Main Group in Vitro

The influence of the main antituberculosis drugs (isoniazid, rifampicin, ethambutol) on in vitro apoptosis of peripheral blood lymphocytes from patients with pulmonary tuberculosis was researched. It was shown that all the investigated drugs induced apoptotic death of the lymphocytes in vitro, that...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Antibiotiki i himioterapiâ 2020-05, Vol.55 (11-12), p.25-29
Hauptverfasser: O. A. Vasilyeva, V. A. Serebryakova, O. I. Urazova, V. V. Novitsky, T. E. Kononova, I. O. Naslednikova
Format: Artikel
Sprache:rus
Schlagworte:
ethambutol
isoniazid
lymphocytes apoptosis
pulmonary tuberculosis
rifampicin
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The influence of the main antituberculosis drugs (isoniazid, rifampicin, ethambutol) on in vitro apoptosis of peripheral blood lymphocytes from patients with pulmonary tuberculosis was researched. It was shown that all the investigated drugs induced apoptotic death of the lymphocytes in vitro, that could result in disturbance of antigen-specific response formation in pulmonary tuberculosis.
ISSN:0235-2990