Fructose metabolism in humans - what isotopic tracer studies tell us

Fructose metabolism in humans - what isotopic tracer studies tell us

Fructose consumption and its implications on public health are currently under study. This work reviewed the metabolic fate of dietary fructose based on isotope tracer studies in humans. The mean oxidation rate of dietary fructose was 45.0% ± 10.7 (mean ± SD) in non-exercising subjects within 3-6 ho...

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Veröffentlicht in:Nutrition & metabolism 2012-10, Vol.9 (1), p.89-89
Hauptverfasser: Sun, Sam Z, Empie, Mark W
Format: Artikel
Sprache:eng
Schlagworte:
Dextrose
Diet
Exercise
Fructose
Fructose metabolism
Genetic aspects
Glucose
Glycogen
Hypotheses
Isotope tracer
Lipids
Liver diseases
Metabolism
Metabolites
Physical fitness
Physiological aspects
Review
Tracers (Biology)
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Zusammenfassung:Fructose consumption and its implications on public health are currently under study. This work reviewed the metabolic fate of dietary fructose based on isotope tracer studies in humans. The mean oxidation rate of dietary fructose was 45.0% ± 10.7 (mean ± SD) in non-exercising subjects within 3-6 hours and 45.8% ± 7.3 in exercising subjects within 2-3 hours. When fructose was ingested together with glucose, the mean oxidation rate of the mixed sugars increased to 66.0% ± 8.2 in exercising subjects. The mean conversion rate from fructose to glucose was 41% ± 10.5 (mean ± SD) in 3-6 hours after ingestion. The conversion amount from fructose to glycogen remains to be further clarified. A small percentage of ingested fructose (
ISSN:1743-7075
1743-7075
DOI:10.1186/1743-7075-9-89