Effects of caloric restriction and ketogenic diet on renal fibrosis after ischemia/reperfusion injury

The beneficial effects of caloric restriction (CR) and a ketogenic diet (KD) have been previously shown when performed prior to kidney injury. We investigated the effects of CR and KD on fibrosis development after unilateral kidney ischemia/reperfusion (UIR). Post-treatment with CR significantly (p ...

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Veröffentlicht in:	Heliyon 2023-11, Vol.9 (11), p.e21003-e21003, Article e21003
Hauptverfasser:	Yakupova, E.I., Semenovich, D.S., Abramicheva, P.A., Zorova, L.D., Pevzner, I.B., Andrianova, N.V., Popkov, V.A., Manskikh, V.N., Bocharnikov, A.D., Voronina, Y.A., Zorov, D.B., Plotnikov, E.Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	blood glucose Caloric restriction fibrosis Glycolysis hydroxyproline ischemia Ischemia/reperfusion injury Ketogenic diet Kidney fibrosis kidneys Krebs cycle lactic acid low calorie diet malate dehydrogenase reperfusion injury succinate dehydrogenase (quinone) Western blotting
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Zusammenfassung:	The beneficial effects of caloric restriction (CR) and a ketogenic diet (KD) have been previously shown when performed prior to kidney injury. We investigated the effects of CR and KD on fibrosis development after unilateral kidney ischemia/reperfusion (UIR). Post-treatment with CR significantly (p
ISSN:	2405-8440 2405-8440
DOI:	10.1016/j.heliyon.2023.e21003