Alpha-gal syndrome

Platts Mills’ research revealed that patients with red meat allergy had a fairly high incidence of α-gal-specific IgE positivity, and the distribution of red meat allergy or higher α-gal-specific IgE coincided with that of the spectrum of Rocky Mountain spotted fever (RMSF) and Amblyomma americanum activity. [1] The first case of red meat allergy in China was reported at the Annual Meeting of the Chinese Allergy Association in 2011. The specific IgE of α-gal, gelatin, cow’s milk, pork, mutton, beef, cat dander, and dog dander was positive in the patients yet they did not manifest immediate-type or delayed-type red meat allergy,[4] which was consistent with previous studies. Human blood type was associated with the prevalence of red meat allergy under an equivalent exposure density of tick bites.