Forensic toxicokinetics of difenidol hydrochloride in vivo verified by practical lethal cases

A gas chromatography-mass spectrometry (GC–MS) method for the determination of difenidol hydrochloride in biological specimens has been developed. The method exhibited excellent recovery (> 90%) and precision (RSD

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Bibliographische Detailangaben
Veröffentlicht in:	Scientific reports 2023-07, Vol.13 (1), p.11190-11190, Article 11190
Hauptverfasser:	Niu, Weifen, Ren, Tongxi, Wang, Yandan, Wang, Zheyu, Zhang, Chao, Jia, Juan, Wei, Zhiwen, Su, Hongliang, Guo, Zhongyuan, Guo, Xiangjie, Yun, Keming
Format:	Artikel
Sprache:	eng
Schlagworte:	631/154/309 631/154/436/1729 631/154/570 Animal models Blood Forensic science Gas chromatography Gastrointestinal tract Heart Humanities and Social Sciences Kidneys Mass spectrometry Mass spectroscopy multidisciplinary Muscles Poisoning Preservation Science Science (multidisciplinary)
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Beschreibung
Zusammenfassung:	A gas chromatography-mass spectrometry (GC–MS) method for the determination of difenidol hydrochloride in biological specimens has been developed. The method exhibited excellent recovery (> 90%) and precision (RSD
ISSN:	2045-2322 2045-2322
DOI:	10.1038/s41598-023-38246-y