Advances in antitumor effects of NSAIDs

Advances in antitumor effects of NSAIDs

In recent years, the reports on using nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer prevention and treatment have been on the rise. In 2017, the US Preventive Services Working Group issued primary prevention guidelines on the use of NSAIDs, especially aspirin, for cardiovascular disease a...

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Veröffentlicht in:Cancer management and research 2018-01, Vol.10, p.4631-4640
Hauptverfasser: Zhang, Zhen, Chen, Fulin, Shang, Lijun
Format: Artikel
Sprache:eng
Schlagworte:
Acids
Analgesics
Analysis
Anti-inflammatory agents
Aspirin
Brain cancer
Cancer
Cancer prevention
Cancer research
Cancer therapies
Cancer treatment
Colorectal cancer
DNA damage
Drug dosages
Drug therapy
Esophageal cancer
Gastric cancer
Growth factors
Health aspects
Health risk assessment
heart failure
Inflammation
Metastasis
nanoparticles
Nonsteroidal anti-inflammatory agents
Nonsteroidal anti-inflammatory drugs
post-infarct ventricular remodeling
Prevention
Preventive medicine
Review
Substance abuse treatment
Tumors
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Zusammenfassung:In recent years, the reports on using nonsteroidal anti-inflammatory drugs (NSAIDs) for cancer prevention and treatment have been on the rise. In 2017, the US Preventive Services Working Group issued primary prevention guidelines on the use of NSAIDs, especially aspirin, for cardiovascular disease and colorectal cancer, and formally established the role and status of aspirin in cancer prevention. However, the mechanism of NSAIDs on preventing cancer is still not clear. In this paper, the progress of the application of NSAIDs, especially aspirin, in the prevention and treatment of tumors in recent years is summarized, and new ideas and directions for the follow-up study are also discussed.
ISSN:1179-1322
1179-1322
DOI:10.2147/CMAR.S175212