Retrospective Analysis of Elderly Patients with Idiopathic Thrombocytopenic Purpura

Material and Methods We performed a retrospective analysis of the 40 consecutive patients that met inclusion criteria over a period of 5 years from May 2015 to March 2020 in Govt Medical College,Jammu. The severity of bleeding ; 1=petechiae; 2=ecchymosis or dripping with moderate blood\loss; 3=bleeding of mucous membranes with copious blood loss without sequellae; 4=bleeding of mucous membranes or the parenchyma with debilitating blood loss and sequellae Inclusion criteria: 1 .thrombocytopenia 2.absence of evidence for dysplasia in peripheral smear 3.no previous treatment with corticosteriods or immunosuppressants Exclusion criteria: 1 .patients on medications like corticosteroids, antiplatelets and immunosupprents 2. presence of dysplasia in lineage apart from megakaryocytic. Maximum number of cases were seen in age group 6570 yrs followed by 70 - 75 yrs with the mean age of presentation being 70 years as depicted in table 2 The initial presentations included: thrombocytopenia revealed by routine blood count or bleeding limited to the skin (bleeding score between 0 to 2) in 15 cases ( 70 %) and severe cutaneous bleeding or visceral bleeding (potentially life-threatening) in one or more other sites (bleeding score 3) in 6cases (15 %) . [251 Conclusion This study involved elderly ITP patients (65 years old) Our results confirm that age influences the hemorrhagic pattern of ITP expression This is why it is suggested that further studies with larger sample sizes and controlled clinical designs are required to improve treatment efficiency for elderly ITP patients.