Multi-institutional analysis of early glottic cancer from 2000 to 2005

The purpose of this study is to analyze the outcome of patients with early glottic cancer (GC) treated with radiotherapy (RT) with or without chemotherapy at 10 institutions in the Tokai District, Japan. Ten institutions combined data from 279 patients with T1-T2 GC treated with RT with or without c...

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Veröffentlicht in:	Radiation oncology (London, England) England), 2012-08, Vol.7 (1), p.122-122, Article 122
Hauptverfasser:	Hirasawa, Naoki, Itoh, Yoshiyuki, Naganawa, Shinji, Ishihara, Shunichi, Suzuki, Kazunori, Koyama, Kazuyuki, Murao, Takayuki, Asano, Akiko, Nomoto, Yoshihito, Horikawa, Yoshimi, Sasaoka, Masahiro, Obata, Yasunori
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Analysis Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer Carboplatin - administration & dosage Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - therapy Care and treatment Chemoradiotherapy Chemotherapy Cisplatin - administration & dosage Docetaxel Female Fluorouracil - administration & dosage Follow-Up Studies Glottic cancer Glottis - pathology Humans Laryngeal Neoplasms - mortality Laryngeal Neoplasms - pathology Laryngeal Neoplasms - therapy Male Middle Aged Multiple institutes Neoplasm Staging Outcomes Patient outcomes Prognosis Radiotherapy Survival Rate Taxoids - administration & dosage Tegafur - administration & dosage Throat cancer Time Factors Uracil - administration & dosage
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Beschreibung
Zusammenfassung:	The purpose of this study is to analyze the outcome of patients with early glottic cancer (GC) treated with radiotherapy (RT) with or without chemotherapy at 10 institutions in the Tokai District, Japan. Ten institutions combined data from 279 patients with T1-T2 GC treated with RT with or without chemotherapy between 2000 and 2005. The overall survival rate, disease-specific survival rate, and local control rate were evaluated in 270 patients, except for incomplete cases due to issues such as discontinuation, using the method of Kaplan-Meier and compared using the log-rank test. Results were considered statistically significant at the level of p
ISSN:	1748-717X 1748-717X
DOI:	10.1186/1748-717X-7-122