Variation in the Lipin 1 Gene Is Associated with Birth Weight and Selected Carcass Traits in New Zealand Romney Sheep
Lipin 1 plays an important role in lipid metabolism. In this study; we searched for variation in the ovine lipin 1 gene ( ) in three gene regions (a 5' non-coding region; a region containing an alternatively spliced exon in intron 4; and a region containing coding exon 6) using polymerase chain...
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Veröffentlicht in: | Animals (Basel) 2020-02, Vol.10 (2), p.237 |
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Sprache: | eng |
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Zusammenfassung: | Lipin 1 plays an important role in lipid metabolism. In this study; we searched for variation in the ovine lipin 1 gene (
) in three gene regions (a 5' non-coding region; a region containing an alternatively spliced exon in intron 4; and a region containing coding exon 6) using polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) analysis. The greatest amount of alleles was found in coding exon 6; with five sequences being detected. The effect of variation in this exon was investigated in 242 New Zealand Romney lambs derived from 12 sire-lines. The presence of variant
was associated with a decrease in birth weight (
= 0.005) and the proportion of leg yield (
= 0.045), but with an increase in hot carcass weight (
= 0.032) and the proportion of loin yield (
= 0.014). The presence of variant
was associated with an increased pre-weaning growth rate (
= 0.041), whereas the presence of variant
was associated with an increase in shoulder yield (
< 0.001). These results suggest that ovine
variation may have value as a genetic marker for improving meat production and carcass traits. |
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ISSN: | 2076-2615 2076-2615 |
DOI: | 10.3390/ani10020237 |