Prognosis-related Factors of Colorectal Cancer Patients with Positive PD-L1 Expression in Liver Metastases After Hepatectomy

Prognosis-related Factors of Colorectal Cancer Patients with Positive PD-L1 Expression in Liver Metastases After Hepatectomy

Objective To evaluate the prognosis-related factors of colorectal cancer patients with positive PD-L1 expression in liver metastases after hepatectomy. Methods We reviewed retrospectively the clinical data of 68 colorectal cancer patients with positive PD-L1 expression in liver metastases receiving...

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Veröffentlicht in:Zhongliu fangzhi yanjiu 2021-08, Vol.48 (8), p.782-787
Hauptverfasser: Zhao, Zhengqiang, Chen, Long, Liu, Yujie, Tian, Suqing
Format: Artikel
Sprache:chi
Schlagworte:
Aquatic birds
Cancer
Colorectal cancer
Colorectal carcinoma
Customization
Health services
Hepatectomy
Liver
liver metastases
Metastases
Metastasis
Mutation
Patients
PD-L1 protein
positive pd-l1 expression
Prognosis
Radiation therapy
surgery
Tumors
Waterfowl
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Zusammenfassung:Objective To evaluate the prognosis-related factors of colorectal cancer patients with positive PD-L1 expression in liver metastases after hepatectomy. Methods We reviewed retrospectively the clinical data of 68 colorectal cancer patients with positive PD-L1 expression in liver metastases receiving personalized comprehensive treatment which was mainly consisted of surgical resection. We observed the results and prognosis after surgical resection and analyzed related factors. Results Univariate analysis showed that no radiotherapy, N stage, RAS mutation status, T stage, dMMR, Duck stage, disease free interval from primary to metastases≤12 months and largest hepatic tumor diameter>5 cm had obvious significance (all P12 months (P=0.020) and largest hepatic tumor diameter
ISSN:1000-8578
DOI:10.3971/j.issn.1000-8578.2021.21.0124