Residual Risk of Trimethylamine‐N‐Oxide and Choline for Stroke Recurrence in Patients With Intensive Secondary Therapy

Residual Risk of Trimethylamine‐N‐Oxide and Choline for Stroke Recurrence in Patients With Intensive Secondary Therapy

Background Trimethylamine N‐oxide (TMAO) contributes to cardiovascular disease through its prothrombotic, proatherothrombotic, and proinflammatory effects. We aimed to evaluate whether residual risk of recurrent stroke of TMAO and its precursor choline remain among patients who received dual‐antipla...

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Veröffentlicht in:Journal of the American Heart Association 2022-10, Vol.11 (19), p.e027265-e027265
Hauptverfasser: Xue, Jing, Xu, Jie, Zhao, Mingming, Jin, Aoming, Cheng, Aichun, Jiang, Xue, Li, Ke, Lin, Jinxi, Meng, Xia, Li, Hao, Zheng, Lemin, Wang, Yongjun
Format: Artikel
Sprache:eng
Schlagworte:
above vs. below the median
choline
ischemic stroke
Original Research
residual risk
stroke recurrence
trimethylamine N‐oxide
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Zusammenfassung:Background Trimethylamine N‐oxide (TMAO) contributes to cardiovascular disease through its prothrombotic, proatherothrombotic, and proinflammatory effects. We aimed to evaluate whether residual risk of recurrent stroke of TMAO and its precursor choline remain among patients who received dual‐antiplatelet therapy and intensive lipid‐lowering therapy and with a low inflammation level (high‐sensitivity C‐reactive protein
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.122.027265