Mycobacterium bolletii respiratory infections

Contrary to other species in the Mycobacterium chelonae-abscessus complex, we reidentified M. bolletii strains isolated from 4 respiratory patients and found these strains to be uniformly resistant to clarithromycin. No mutations previously associated with macrolide resistance in bacteria were detec...

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Veröffentlicht in:	Emerging infectious diseases 2009-02, Vol.15 (2), p.302-305
Hauptverfasser:	Adékambi, Toïdi, Drancourt, Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Anti-Bacterial Agents - pharmacology Antibacterial agents Antitubercular Agents - pharmacology Antitubercular Agents - therapeutic use Dispatch DNA, Bacterial - analysis DNA, Ribosomal Drug resistance in microorganisms Fatal Outcome Female France Health aspects Humans Lung diseases M. chelonae-abscessus group Male Microbial Sensitivity Tests Middle Aged Mycobacterium Mycobacterium - classification Mycobacterium - drug effects Mycobacterium - genetics Mycobacterium - isolation & purification Mycobacterium bolletti Mycobacterium Infections - drug therapy Mycobacterium Infections - microbiology respiratory infections Respiratory Tract Infections - drug therapy Respiratory Tract Infections - microbiology RNA, Ribosomal, 23S - genetics Sequence Analysis, DNA Sputum - microbiology Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - microbiology
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Zusammenfassung:	Contrary to other species in the Mycobacterium chelonae-abscessus complex, we reidentified M. bolletii strains isolated from 4 respiratory patients and found these strains to be uniformly resistant to clarithromycin. No mutations previously associated with macrolide resistance in bacteria were detected in either the 23S rDNA or the genes encoding riboproteins L4 and L22.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid1502.080837