Ureaplasma urealyticum osteomyelitis of the greater trochanter in a patient with multiple sclerosis using ocrelizumab - a case report

Ocrelizumab - a monoclonal anti-CD20 antibody used in treatment of multiple sclerosis (MS) - marks significant progress in treating autoimmune diseases but raises susceptibility to opportunistic infections due to hypogammaglobulinemia. A young MS patient developed osteomyelitis from persistent ureth...

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Veröffentlicht in:Journal of bone and joint infection 2024-06, Vol.9 (3), p.167-171
Hauptverfasser: Ruythooren, Fred, Ghijselings, Stijn, Depypere, Melissa, Metsemakers, Willem-Jan, Henckaerts, Liesbet, Noppe, Nathalie, Vles, Georges
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Sprache:eng
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Zusammenfassung:Ocrelizumab - a monoclonal anti-CD20 antibody used in treatment of multiple sclerosis (MS) - marks significant progress in treating autoimmune diseases but raises susceptibility to opportunistic infections due to hypogammaglobulinemia. A young MS patient developed osteomyelitis from persistent urethritis, which was diagnosed with specialized polymerase chain reaction and resolved with targeted antibiotics. A multidisciplinary approach is crucial for managing such infections.
ISSN:2206-3552
2206-3552
DOI:10.5194/jbji-9-167-2024