Replication-Competent Oropouche Virus in Semen of Traveler Returning to Italy from Cuba, 2024

A febrile man in Italy who had traveled to Cuba in July 2024 was diagnosed with Oropouche fever. Reverse transcription PCR detected prolonged shedding of Oropouche virus RNA in whole blood, serum, urine, and semen. Sixteen days after symptom onset, replication-competent virus was detected in semen,...

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Veröffentlicht in:	Emerging infectious diseases 2024-12, Vol.30 (12), p.2684-2686
Hauptverfasser:	Castilletti, Concetta, Huits, Ralph, Mantovani, Rebeca Passarelli, Accordini, Silvia, Alladio, Francesca, Gobbi, Federico
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Arbovirus diseases arboviruses bunyaviridae infections Bunyaviridae Infections - virology Care and treatment Competent Oropouche Virus in Semen of Traveler Returning to Italy from Cuba, 2024 Cuba - epidemiology Diagnosis Distribution Editing Epidemiology Fever Funding Hospitals Humans Infections isolation and purification Italy - epidemiology Male Methods Oropouche virus Orthobunyavirus - classification Orthobunyavirus - genetics Orthobunyavirus - isolation & purification Polymerase chain reaction reproductive health Reproductive technologies Research Letter RNA, Viral - genetics semen Semen - virology Thrombocytopenia Travel Urine Virus Replication Zika virus
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Zusammenfassung:	A febrile man in Italy who had traveled to Cuba in July 2024 was diagnosed with Oropouche fever. Reverse transcription PCR detected prolonged shedding of Oropouche virus RNA in whole blood, serum, urine, and semen. Sixteen days after symptom onset, replication-competent virus was detected in semen, suggesting risk for sexual transmission.
ISSN:	1080-6040 1080-6059 1080-6059
DOI:	10.3201/eid3012.241470