Association between serum netrin-1 levels and early neurological deterioration after acute ischemic stroke

Background and purposesExperimental studies demonstrated that netrin-1 (NT-1) has anti-inflammatory, tissue regeneration, and immune modulation properties. We aimed to discern the utility of NT-1 as a biomarker for assessing the risk of early neurological deterioration (END) after ischemic stroke. M...

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Veröffentlicht in:	Frontiers in neurology 2022-08, Vol.13, p.953557-953557
Hauptverfasser:	Chen, Zhuo, Cao, Tianli, Zhong, Xingju, Wu, Yong, Fu, Wei, Fan, Chaoli, Jiang, Yu, Zhou, Qi, Peng, Jie, Liao, Jieyu, You, Zhike, Yi, Xin, Tan, Jingyu
Format:	Artikel
Sprache:	eng
Schlagworte:	acute ischemic stroke biomarker early neurological deterioration netrin-1 Neurology restricted cubic spline
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Beschreibung
Zusammenfassung:	Background and purposesExperimental studies demonstrated that netrin-1 (NT-1) has anti-inflammatory, tissue regeneration, and immune modulation properties. We aimed to discern the utility of NT-1 as a biomarker for assessing the risk of early neurological deterioration (END) after ischemic stroke. MethodsThis was a prospective study enrolling ischemic stroke patients with symptoms onset
ISSN:	1664-2295 1664-2295
DOI:	10.3389/fneur.2022.953557