Zero-Contrast Conscious Sedation Transcatheter Aortic Valve Replacement—Keeping It Safe and Simple

1.Contrast-free transfemoral transcatheter aortic valve replacement was performed in a case series of 4 patients using a novel technique guided by transthoracic echocardiography under conscious sedation.2.Outcomes including mortality, incidence of cerebrovascular accident, or heart block were comparable with those of the traditional approach while minimizing the risk of renal injury.3.This approach gives the heart team a technically feasible, safe, and effective option to minimize the risk of renal injury, the need for transesophageal echocardiogram, and higher levels of sedation.