Сocrystals of betulin with suberic acid: mechanochemical synthesis and thermal behavior

In this work, the cocrystals of betulin with suberic acid were prepared by liquid-assisted grinding method using solvents of different polarity. The formation of cocrystals was confirmed by means of powder X-ray diffraction, IR spectroscopy and thermal analysis. It was shown that under heating, a st...

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Veröffentlicht in:MATEC web of conferences 2021, Vol.340, p.1019
Hauptverfasser: Mikhailovskaya, Anastasiya, Myz, Svetlana, Gerasimov, Konstantin, Kuznetsova, Svetlana, Shakhtshneider, Tatyana
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Sprache:eng
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Zusammenfassung:In this work, the cocrystals of betulin with suberic acid were prepared by liquid-assisted grinding method using solvents of different polarity. The formation of cocrystals was confirmed by means of powder X-ray diffraction, IR spectroscopy and thermal analysis. It was shown that under heating, a structural transformation occurred after water removal, followed by cocrystal dissociation.
ISSN:2261-236X
2274-7214
2261-236X
DOI:10.1051/matecconf/202134001019