Neuroinvasion by Mycoplasma pneumoniae in acute disseminated encephalomyelitis

Neuroinvasion by Mycoplasma pneumoniae in acute disseminated encephalomyelitis

We report the autopsy findings for a 45-year-old man with polyradiculoneuropathy and fatal acute disseminated encephalomyelitis after having Mycoplasma pneumoniae pneumonia. M. pneumoniae antigens were demonstrated by immunohistochemical analysis of brain tissue, indicating neuroinvasion as an addit...

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Veröffentlicht in:Emerging infectious diseases 2008-04, Vol.14 (4), p.641-643
Hauptverfasser: Stamm, Bernhard, Moschopulos, Michael, Hungerbuehler, Hansjoerg, Guarner, Jeannette, Genrich, Gillian L, Zaki, Sherif R
Format: Artikel
Sprache:eng
Schlagworte:
Acute Disease
acute hemorrhagic
Antibacterial agents
Antibodies, Bacterial - blood
Antibodies, Bacterial - cerebrospinal fluid
Antigens, Bacterial - isolation & purification
Bacterial pneumonia
Brain - microbiology
Brain - pathology
Dispatch
Encephalomyelitis
Encephalomyelitis - complications
Encephalomyelitis - microbiology
Encephalomyelitis - pathology
Fatal Outcome
Health aspects
Humans
Hurst disease
Immunohistochemistry
leukoencephalitis
Male
Middle Aged
Mycoplasma pneumoniae
Mycoplasma pneumoniae - immunology
Mycoplasma pneumoniae - isolation & purification
Mycoplasma pneumoniae encephalomyelitis acute disseminated
Pneumonia
Pneumonia, Mycoplasma - complications
Polyradiculoneuropathy - complications
Polyradiculoneuropathy - microbiology
Polyradiculoneuropathy - pathology
Switzerland
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Zusammenfassung:We report the autopsy findings for a 45-year-old man with polyradiculoneuropathy and fatal acute disseminated encephalomyelitis after having Mycoplasma pneumoniae pneumonia. M. pneumoniae antigens were demonstrated by immunohistochemical analysis of brain tissue, indicating neuroinvasion as an additional pathogenetic mechanism in central neurologic complications of M. pneumoniae infection.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid1404.061366