EFFECT OF EPINEPHRINE ADMINISTRATION ON MYOCARDIAL REMODELING IN EXPERIMENTAL STUDY

EFFECT OF EPINEPHRINE ADMINISTRATION ON MYOCARDIAL REMODELING IN EXPERIMENTAL STUDY

Aim. To study structural changes in the myocardium of Wistar rats after a single administration of epinephrine.Material and methods. Structural changes in male Wistar rat’s left (LV) and right (RV) ventricle myocardium after a single injection of epinephrine were studied.Results. The density of extr...

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Veröffentlicht in:Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii 2017-01, Vol.13 (3), p.378-382
Hauptverfasser: Veber, V. R., Zhmailova, S. V., Rubanova, M. P., Gubskaya, P. M.
Format: Artikel
Sprache:eng
Schlagworte:
epinephrine
left ventricle
myocardial remodeling
myocardium
right ventricle
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Zusammenfassung:Aim. To study structural changes in the myocardium of Wistar rats after a single administration of epinephrine.Material and methods. Structural changes in male Wistar rat’s left (LV) and right (RV) ventricle myocardium after a single injection of epinephrine were studied.Results. The density of extracellular spaces in bothLV and RV myocardium increases first after single epinephrine injection (after 2 hours), and then-decreases below reference values in the next control points. It remains so even after 1 month after a single injection of epinephrine in both theLV (3.95±0.64-vs 6.83±0.30 vol% in the control group; p
ISSN:1819-6446
2225-3653
DOI:10.20996/1819-6446-2017-13-3-378-382