The value of observational registry studies for the next infectious disease emergency

The value of observational registry studies for the next infectious disease emergency

During infectious disease emergencies, it may be necessary to deploy new therapies without conclusive evidence for their effectiveness. During the SARS-CoV-2 pandemic, several countries used registries to track the use of COVID-19 convalescent plasma (CCP). Those registries provided evidence that CC...

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Veröffentlicht in:mBio 2023-12, Vol.14 (6), p.e0256523
Hauptverfasser: Senefeld, Jonathon W, Marks, Peter, Casadevall, Arturo, Joyner, Michael J
Format: Artikel
Sprache:eng
Schlagworte:
clinical trials
coronavirus
COVID-19 - epidemiology
COVID-19 - therapy
COVID-19 Serotherapy
Editorial
Emergencies
Humans
Immunization, Passive
Immunology
neutralizing antibodies
Observational Studies as Topic
Pandemics
Registries
SARS-CoV-2
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Beschreibung
Zusammenfassung:During infectious disease emergencies, it may be necessary to deploy new therapies without conclusive evidence for their effectiveness. During the SARS-CoV-2 pandemic, several countries used registries to track the use of COVID-19 convalescent plasma (CCP). Those registries provided evidence that CCP was effective when used early and with high titer.
ISSN:2150-7511
2150-7511
DOI:10.1128/mbio.02565-23