Percutaneous vertebroplasty combined with chemotherapy in the treatment of multiple myeloma patients with vertebral compression fractures

[1] MM-associated VCFs cause spinal instability, back pain, spinal kyphosis, neurologic dysfunction, and subsequent respiratory complications, which markedly decrease the quality of life of affected patients. [2] In recent years, preliminary studies have demonstrated the effectiveness of PVP or PKP in controlling the pain and improving the quality of life of patients with MM-associated VCFs. Quality of life was measured by the Oswestry Disability Index (ODI), which represents the level of disability on a scale ranging from 0% (no disability) to 100% (bed-bound). Each clinical variable was recorded before treatment, at 1 day, 1 month, 6 months, and 12 months after treatment, and at final follow-up.