Adenosquamous carcinoma of the liver

PATHOLOGIC FINDINGS Gross examination revealed multiple whitish solid masses with spongiform appearance (Fig. 1B). [...]multiple foci were present that showed microcystic change with spongiform appearance. Histologically, most of the cysts were lined with polygonal cells with prominent nuclear atypia and a few cystic spaces contained keratin material, suggestive of cystic degeneration of squamous cell carcinoma areas. [...]we postulated that the present ASC case predominantly consisted of squamous cell carcinoma components, and that the cystic changes in the squamous cell carcinoma components resulted in the microcystic change.