Association between Plasmatic Ceramides Profile and AST/ALT Ratio: C14:0 Ceramide as Predictor of Hepatic Steatosis in Adolescents Independently of Obesity

Objective. To assess the association between plasma ceramides and hepatic steatosis (HS) in adolescents, independently of obesity. Materials and Methods. Ninety-four adolescents from two previous studies conducted and published by our crew were included. Study subjects were stratified in three group...

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Veröffentlicht in:	Canadian journal of gastroenterology & hepatology 2017-01, Vol.2017 (2017), p.1-6
Hauptverfasser:	Núñez-García, Benjamín A., Piña-Aguero, Mónica I., Saldaña-Dávila, Gabriela E., Maldonado-Hernández, Jorge, López-Alarcón, Mardia
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Alanine Transaminase - blood Apoptosis Aspartate Aminotransferases - blood Biomarkers Biomarkers - blood Care and treatment Ceramides Ceramides - blood Diagnosis Disease Fasting - blood Fatty acids Fatty Liver - blood Fatty Liver - etiology Female Health aspects Humans Inflammation Insulin - blood Insulin resistance Liver Liver diseases Male Metabolism Methods Obesity Pediatric Obesity - blood Pediatric Obesity - complications Pediatrics Physiological aspects Population Predictive Value of Tests Rodents Sensitivity and Specificity Studies Teenagers Transaminases
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Zusammenfassung:	Objective. To assess the association between plasma ceramides and hepatic steatosis (HS) in adolescents, independently of obesity. Materials and Methods. Ninety-four adolescents from two previous studies conducted and published by our crew were included. Study subjects were stratified in three groups: normal weight (n=18), obesity (n=34), and obesity + HS (n=42). The presence of HS was defined when ALT/AST ratio was
ISSN:	2291-2789 2291-2797
DOI:	10.1155/2017/3689375