Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT

Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT

Background Intensive systolic blood pressure ( SBP ) lowering significantly reduced cardiovascular disease ( CVD ) events in SPRINT (Systolic Blood Pressure Intervention Trial) but not in ACCORD BP (Action to Control Cardiovascular Risk in Diabetes Blood Pressure). Methods and Results SPRINT tested...

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Veröffentlicht in:Journal of the American Heart Association 2018-09, Vol.7 (18), p.e009326
Hauptverfasser: Beddhu, Srinivasan, Chertow, Glenn M, Greene, Tom, Whelton, Paul K, Ambrosius, Walter T, Cheung, Alfred K, Cutler, Jeffrey, Fine, Lawrence, Boucher, Robert, Wei, Guo, Zhang, Chong, Kramer, Holly, Bress, Adam P, Kimmel, Paul L, Oparil, Suzanne, Lewis, Cora E, Rahman, Mahboob, Cushman, William C
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Antihypertensive Agents - administration & dosage
Blood Glucose - drug effects
Blood Glucose - metabolism
Blood Pressure - drug effects
Cardiovascular Diseases - blood
Cardiovascular Diseases - complications
Cardiovascular Diseases - epidemiology
cardiovascular outcomes
diabetes mellitus
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - drug therapy
Diabetes Mellitus, Type 2 - mortality
Dose-Response Relationship, Drug
Drug Therapy, Combination
Female
Fenofibrate - administration & dosage
high blood pressure
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage
hypertension
Hypolipidemic Agents
Incidence
Male
Middle Aged
Original Research
Prognosis
Risk Factors
Simvastatin - administration & dosage
Survival Rate - trends
Treatment Outcome
United States - epidemiology
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Zusammenfassung:Background Intensive systolic blood pressure ( SBP ) lowering significantly reduced cardiovascular disease ( CVD ) events in SPRINT (Systolic Blood Pressure Intervention Trial) but not in ACCORD BP (Action to Control Cardiovascular Risk in Diabetes Blood Pressure). Methods and Results SPRINT tested the effects of intensive (
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.118.009326