Human leukocyte antigen profile of two ethnic groups in Southeast of Iran

This study was performed to determine the genetic diversity of HLA class I and II alleles among two ethnic groups in Southeastern Iran. HLA profiles were determined in 71 Iranian populations (41 Zaboli and 30 Baloch). The frequencies of HLA-A02 (p=0.017), -Cw4 (p=0.003), and -DR8 (p=0.025) in the Za...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Iranian journal of allergy, asthma, and immunology asthma, and immunology, 2007-12, Vol.6 (4), p.223-224
Hauptverfasser:	Khazaei, Hossein Ali, Rezaei, Nima, Aghamohammadi, Asghar, Amirzargar, Ali Akbar, Ghasemi, Khadidjeh, Mirimoghaddam, Ibrahim, Nikbin, Behrouz
Format:	Artikel
Sprache:	eng
Schlagworte:	Ethnic Groups Genetics, Population Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - immunology Histocompatibility Antigens Class II - genetics Histocompatibility Antigens Class II - immunology Humans Iran
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This study was performed to determine the genetic diversity of HLA class I and II alleles among two ethnic groups in Southeastern Iran. HLA profiles were determined in 71 Iranian populations (41 Zaboli and 30 Baloch). The frequencies of HLA-A02 (p=0.017), -Cw4 (p=0.003), and -DR8 (p=0.025) in the Zaboli populations were significantly higher than that in Baloch ethnic group. In contrast, the frequency of HLA-A23 allele was more frequent in Baloch than Zaboli (p=0.020). This report represents an important resource for investigators in the fields of transplantation immunology and population genetics from widely dispersed areas of Iran.
ISSN:	1735-1502 1735-5249