Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09

Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09

We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. I...

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Veröffentlicht in:Emerging infectious diseases 2024-01, Vol.30 (1), p.168-171
Hauptverfasser: Daulagala, Pavithra, Cheng, Samuel M S, Chin, Alex, Luk, Leo L H, Leung, Kathy, Wu, Joseph T, Poon, Leo L M, Peiris, Malik, Yen, Hui-Ling
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Avian flu
Birds
Blood & organ donations
clade 2.3.4.4.b
Dispatch
Health care
Infections
influenza
influenza A(H1N1)pdm09
influenza A(H5N1)
Pandemics
Proteins
respiratory infections
Risk assessment
Surveillance
Vaccines
Viruses
Zoonoses
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Zusammenfassung:We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, antibodies at low titers were detected in 42% (21/50) of serum samples collected in 2009. Influenza A(H1N1)pdm09 and A(H5N1) titers were correlated.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid3001.230756