The efficacy of low-intensity transcranial ultrasound stimulation on negative symptoms in schizophrenia: A double-blind, randomized sham-controlled study

The efficacy of low-intensity transcranial ultrasound stimulation on negative symptoms in schizophrenia: A double-blind, randomized sham-controlled study

•rTUS over the left dorsolateral prefrontal cortex (DLPFC) can alleviate the negative symptoms in schizophrenia.•Fifteen-sessions rTUS over left DLPFC enhances the performance of the Continuous Performance Test in schizophrenia.•rTUS intervention induces long-term potentiation like (LTP-like) plasti...

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Veröffentlicht in:Brain stimulation 2023-05, Vol.16 (3), p.790-792
Hauptverfasser: Zhai, Zhaolin, Ren, Liyuan, Song, Zhenhua, Xiang, Qiong, Zhuo, Kaiming, Zhang, Suzhen, Li, Xuan, Zhang, Yi, Jiao, Xiong, Tong, Shanbao, Sun, Junfeng, Liu, Dengtang
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Sprache:eng
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Zusammenfassung:•rTUS over the left dorsolateral prefrontal cortex (DLPFC) can alleviate the negative symptoms in schizophrenia.•Fifteen-sessions rTUS over left DLPFC enhances the performance of the Continuous Performance Test in schizophrenia.•rTUS intervention induces long-term potentiation like (LTP-like) plasticity.•No serious adverse events (AEs) have been reported.
ISSN:1935-861X
1876-4754
DOI:10.1016/j.brs.2023.04.021