WU polyomavirus in respiratory epithelial cells from lung transplant patient with Job syndrome

We detected WU polyomavirus (WUPyV) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with Job syndrome by using immunoassays specific for the WUPyV viral protein 1. Co-staining for an epithelial cell marker identified most WUPyV viral protein 1-positive cells as respirator...

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Veröffentlicht in:	Emerging infectious diseases 2015-01, Vol.21 (1), p.103-106
Hauptverfasser:	Siebrasse, Erica A, Pastrana, Diana V, Nguyen, Nang L, Wang, Annie, Roth, Mark J, Holland, Steven M, Freeman, Alexandra F, McDyer, John, Buck, Christopher B, Wang, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Dispatch Female Health aspects HEK293 Cells Humans immunosuppression Infection Job Syndrome - surgery Job Syndrome - virology Lung Transplantation Polyomavirus - genetics Polyomavirus - isolation & purification Polyomavirus Infections - diagnosis Polyomavirus Infections - virology respiratory epithelial cells Respiratory Mucosa - virology Skin transplant Transplantation of organs, tissues, etc tropism viruses WU polyomavirus WU Polyomavirus in Respiratory Epithelial Cells from Lung Transplant Patient with Job Syndrome
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Zusammenfassung:	We detected WU polyomavirus (WUPyV) in a bronchoalveolar lavage sample from lungs transplanted into a recipient with Job syndrome by using immunoassays specific for the WUPyV viral protein 1. Co-staining for an epithelial cell marker identified most WUPyV viral protein 1-positive cells as respiratory epithelial cells.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2101.140855