Multiscale optoacoustic assessment of skin microvascular reactivity in carotid artery disease

Multiscale optoacoustic assessment of skin microvascular reactivity in carotid artery disease

Microvascular endothelial dysfunction may provide insights into systemic diseases, such as carotid artery disease. Raster-scan optoacoustic mesoscopy (RSOM) can produce images of skin microvasculature during endothelial dysfunction challenges via numerous microvascular features. Herein, RSOM was emp...

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Veröffentlicht in:Photoacoustics (Munich) 2024-12, Vol.40, p.100660, Article 100660
Hauptverfasser: Karlas, Angelos, Katsouli, Nikoletta, Fasoula, Nikolina-Alexia, Reidl, Mario, Lees, Rhiannon, Zang, Lan, Carrillo, Maria del Pilar Ortega, Saicic, Stefan, Schäffer, Christoph, Hadjileontiadis, Leontios, Branzan, Daniela, Ntziachristos, Vasilis, Eckstein, Hans-Henning, Kallmayer, Michael
Format: Artikel
Sprache:eng
Schlagworte:
Cardiovascular disease
Microvascular endothelial dysfunction
Microvascular features
Non-invasive imaging
Raster-scan optoacoustic mesoscopy
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Zusammenfassung:Microvascular endothelial dysfunction may provide insights into systemic diseases, such as carotid artery disease. Raster-scan optoacoustic mesoscopy (RSOM) can produce images of skin microvasculature during endothelial dysfunction challenges via numerous microvascular features. Herein, RSOM was employed to image the microvasculature of 26 subjects (13 patients with single carotid artery disease, 13 healthy participants) to assess the dynamics of 18 microvascular features at three scales of detail, i.e., the micro- (
ISSN:2213-5979
2213-5979
DOI:10.1016/j.pacs.2024.100660