Prognostic factors for hepatocellular carcinoma recurrence after liver transplantation or resection – single-center experience

The aim of the study was to assess prognostic factors associated with an increased risk of recurrence of hepatocellular carcinoma (HCC) after radical treatment. This is a retrospective, single-center analysis of data on HCC recurrence in patients who underwent radical treatment. Molecular tumor characteristics, baseline laboratory results and hepatic viral status were analyzed. Data from 111 patients were included in the analysis. The most important prognostic factors for recurrence were vascular microinvasion (HR 4.54; 95 % CI 1.769–11.681; p 0.001), baseline white blood count (HR 2.13; 95 % CI 1.261–3.567; p 0.004) and baseline alpha-fetoprotein (HR 1.00009; 95 % CI 1.000001–1.00002; p 0.034). Microvascular invasion was only prognostic factor which correlate significantly with the overall survival (HR 5.04, 95 % CI 2.352–12.413; p