Research progress of RNA binding motif protein family-mediated alternative splicing in cardiomyopathy

RNA binding motif protein (RBM) is a type of RNA binding protein, which contains RNA recognition motif, RNA binding motif and ribo-nucleo-protein motif. The alternative splicing mediated by members of the RBM family is closely related to myocardial contractile proteins, myocardial development and my...

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Veröffentlicht in:Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics 2022-08, Vol.42 (8), p.1274-1278
1. Verfasser: LIU Shu, DING Hong, ZHAO Ke-xin, BAI Feng, ZHANG Xiao-wei
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Sprache:chi
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Zusammenfassung:RNA binding motif protein (RBM) is a type of RNA binding protein, which contains RNA recognition motif, RNA binding motif and ribo-nucleo-protein motif. The alternative splicing mediated by members of the RBM family is closely related to myocardial contractile proteins, myocardial development and myocardial sodium channels, which play an important role in pathogenesis of myocardial diseases and even heart failure.
ISSN:1001-6325
DOI:10.16352/j.issn.1001-6325.2022.08.1274