Clinicopathological variables influencing overall survival, recurrence and post-recurrence survival in resected stage I non-small-cell lung cancer

To investigate clinicopathological variables influencing overall survival, overall recurrence, and post-recurrence survival (PRS) in patients who experienced curative-intent surgical resection of stage I non-small-cell lung cancer (NSCLC). We investigated a series of 1387 patients with stage I NSCLC...

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Veröffentlicht in:BMC cancer 2020-02, Vol.20 (1), p.150-150, Article 150
Hauptverfasser: Wang, Chengdi, Wu, Yuxuan, Shao, Jun, Liu, Dan, Li, Weimin
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Sprache:eng
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Zusammenfassung:To investigate clinicopathological variables influencing overall survival, overall recurrence, and post-recurrence survival (PRS) in patients who experienced curative-intent surgical resection of stage I non-small-cell lung cancer (NSCLC). We investigated a series of 1387 patients with stage I NSCLC who underwent surgical resection from 2008 to 2015. The effect clinicopathological factors on death, recurrence, and PRS were evaluated by Kaplan-Meier estimates and cox regression analysis. Among the 1387 stage I patients, 301 (21.7%) experienced recurrence. The 5-year cumulative incidence of recurrence (CIR) for all patients was 20.2% and median PRS was 25.5 months. The older age (P = 0.036), p-stage IB (P = 0.001), sublobar resection(P
ISSN:1471-2407
1471-2407
DOI:10.1186/s12885-020-6621-1