Antibacterial Composite Layers on Ti: Role of ZnO Nanoparticles
Problem of post-operative infections of implant materials caused by bacterial adhesion to their surfaces is very serious. Enhancement of antibacterial properties is potentially beneficial for biomaterials value. Therefore, the metallic and metallic oxide nanoparticles attract particular attention as...
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Veröffentlicht in: | Archives of metallurgy and materials 2016-06, Vol.61 (2), p.937-940 |
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Sprache: | eng |
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Zusammenfassung: | Problem of post-operative infections of implant materials caused by bacterial adhesion to their surfaces is very serious. Enhancement of antibacterial properties is potentially beneficial for biomaterials value. Therefore, the metallic and metallic oxide nanoparticles attract particular attention as antimicrobial factors. The aim of this work was to create nanotubular (NT) oxide layers on Ti with the addition of ZnO nanoparticles, designed for antibacterial biomedical coatings. Antimicrobial activities of titanium, TiO
NT and ZnO/TiO
NT surfaces were evaluated against bacterial strain typical for orthopaedic infections: S. epidermidis. TiO
NT alone killed the free bacterial cells significantly but promoted their adhesion to the surfaces. The presence of moderate amount of ZnO nanoparticles significantly reduced the S. epidermidis cells adhesion and viability of bacterial cells in contact with modified surfaces. However, higher amount of loaded nanoZnO showed the reduced antimicrobial properties than the medium amount, suggesting the overdose effect. |
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ISSN: | 2300-1909 1733-3490 2300-1909 |
DOI: | 10.1515/amm-2016-0159 |