An alternative synthesis of Azilsartan: an angiotensin II receptor blocker

An alternative synthesis of Azilsartan: an angiotensin II receptor blocker

This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a pro-drug of Azilsartan medoxomil, an angiotensin II receptor blocker. The present work also provides a primary account of the synthesis and charact...

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Veröffentlicht in:Current issues in pharmacy and medical sciences 2015-06, Vol.28 (2), p.72-76
Hauptverfasser: Garaga, Srinivas, Misra, Nimesh C., Reddy, Ambati V. Raghava, Prabahar, Koilpillai Joseph, Takshinamoorthy, Chandiran, Sanasi, Paul Douglas, Korupolu, Raghubabu
Format: Artikel
Sprache:eng
Schlagworte:
Azilsartan
novel intermediates
synthesis and characterization
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Zusammenfassung:This paper provides a description of an alternative, novel and commercially viable process which has been developed for the preparation of Azilsartan, a pro-drug of Azilsartan medoxomil, an angiotensin II receptor blocker. The present work also provides a primary account of the synthesis and characterization of the novel intermediates (6, 7 & 10) of Azilsartan, with their spectral data.
ISSN:2084-980X
2300-6676
DOI:10.1515/cipms-2015-0047