Laser assisted pulmonary metastasectomy promises a low local recurrence rate

Pulmonary metastasectomy (PM) is consensually performed in a parenchyma-sparing manner to preserve functionally healthy lung tissue. However, this may increase the risk of local recurrence at the surgical margin. Laser assisted pulmonary metastasectomy (LPM) is a relatively recent innovation that is...

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Veröffentlicht in:Scientific reports 2024-03, Vol.14 (1), p.5988-5988, Article 5988
Hauptverfasser: Shalabi, Ahmad, Ehab, Ahmed, Shalabi, Sundus F., Kugler, Gudrun, Schäfers, H.-J., Graeter, Thomas
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Sprache:eng
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Zusammenfassung:Pulmonary metastasectomy (PM) is consensually performed in a parenchyma-sparing manner to preserve functionally healthy lung tissue. However, this may increase the risk of local recurrence at the surgical margin. Laser assisted pulmonary metastasectomy (LPM) is a relatively recent innovation that is especially useful to resect multiple metastatic pulmonary nodules. In this study we investigated the rate of local recurrence after LPM and evaluated the influence of various clinical and pathological factors on local recurrence. Retrospectively, a total of 280 metastatic nodules with different histopathological entities were studied LPM from 2010 till 2018. All nodules were resected via diode-pumped neodymium: yttrium–aluminum-garnet (Nd:YAG) 1,318 nm laser maintaining a safety margin of 5 mm. Patients included were observed on average for 44 ± 17 months postoperatively. Local recurrence at the surgical margin following LPM was found in 9 nodules out of 280 nodules (3.21%). Local recurrence at the surgical margin occurred after 20 ± 8.5 months post operation. Incomplete resection ( p  =  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-024-56566-5