Characteristics of diabetic macular edema on optical coherence tomography may change over time or after treatment

To investigate optical coherence tomography (OCT) characteristics in diabetic macular edema (DME) over time and after treatment. OCT morphological features in DME eyes treated with ranibizumab with at least 1 year of follow-up were retrospectively analyzed. Thirty-five eyes were included. From basel...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical ophthalmology (Auckland, N.Z.) N.Z.), 2018-01, Vol.12, p.1887-1893
Hauptverfasser:	Sheu, Shwu-Jiuan, Lee, Ying-Yen, Horng, Yu-Harn, Lin, Huey-Shyan, Lai, Wei-Yu, Tsen, Chui-Lien
Format:	Artikel
Sprache:	eng
Schlagworte:	Aflibercept Bevacizumab Biomarkers Clinical trials Diabetes diabetic macular edema Diabetic retinopathy Edema Endothelial growth factors Endothelium Medical imaging Monoclonal antibodies Morphology Ophthalmology Optical Coherence Tomography (OCT) Original Research Photoreceptors Ranibizumab subretinal fluid (SRF) Tomography Type 2 diabetes Variance analysis Vascular endothelial growth factor vascular endothelial growth factor (VEGF)
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	To investigate optical coherence tomography (OCT) characteristics in diabetic macular edema (DME) over time and after treatment. OCT morphological features in DME eyes treated with ranibizumab with at least 1 year of follow-up were retrospectively analyzed. Thirty-five eyes were included. From baseline to Month 12, mean visual gain was 7.2±13.6 letters and mean central retinal thickness reduction was 61.9±121.8 μm. Fovea-involving ellipsoid zone (EZ) disruption was significantly associated with final vision of
ISSN:	1177-5467 1177-5483 1177-5483
DOI:	10.2147/OPTH.S173956