Effectiveness of Meningococcal B Vaccine against Endemic Hypervirulent Neisseria meningitidis W Strain, England

Serum samples from children immunized with a meningococcal serogroup B vaccine demonstrated potent serum bactericidal antibody activity against the hypervirulent Neisseria meningitidis serogroup W strain circulating in England. The recent introduction of this vaccine into the United Kingdom national...

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Veröffentlicht in:	Emerging infectious diseases 2016-02, Vol.22 (2), p.309-311
Hauptverfasser:	Ladhani, Shamez N, Giuliani, Marzia Monica, Biolchi, Alessia, Pizza, Mariagrazia, Beebeejaun, Kazim, Lucidarme, Jay, Findlow, Jamie, Ramsay, Mary E, Borrow, Ray
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Bacterial - blood Antibodies, Bacterial - immunology Bacterial vaccines Cross Reactions - immunology Dispatch Effectiveness of Meningococcal B Vaccine against Endemic Hypervirulent Neisseria meningitidis W Strain, England Humans Infant Infant, Newborn Meningitis, Meningococcal - prevention & control Meningococcal infections Meningococcal Vaccines - immunology meningococcal W disease meningococci, serum bactericidal antibody (SBA) activity, immunization, endemic, meningitis, Bexsero, Menveo, England Neisseria meningitidis Neisseria meningitidis - classification Neisseria meningitidis - genetics Neisseria meningitidis - immunology Neisseria meningitidis, meningococcal W disease Prevention ST-11 clonal complex Testing United Kingdom - epidemiology Vaccination
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Beschreibung
Zusammenfassung:	Serum samples from children immunized with a meningococcal serogroup B vaccine demonstrated potent serum bactericidal antibody activity against the hypervirulent Neisseria meningitidis serogroup W strain circulating in England. The recent introduction of this vaccine into the United Kingdom national immunization program should also help protect infants against this endemic strain.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2202.150369