Retrospective Analysis of Antibiotic Resistance in Streptococcus spp. from HIV Patients (2012-2017) from Southern India

Centers for Disease Control and Prevention (CDC) categorized drug-resistant S. pneumoniae as seriously hazardous bacteria, and erythromycin-resistant Streptococcus Group A and clindamycin-resistant Streptococcus Group B under the hazardous level category, which is concerning. Antibiotic susceptibility testing of Streptococcus pyogenes and α-hemolytic Streptococcus spp. was performed by Kirby–Bauer disc diffusion method[3] using antibiotics such as ampicillin (10 μg), cefepime (30 μg), ceftriaxone (30 μg), cefotaxime (30 μg), chloramphenicol (30 μg), clindamycin (2 μg), erythromycin (15 μg), levofloxacin (5 μg), ofloxacin (5 μg), penicillin (10 units), and vancomycin (30 μg), and the results were analyzed. World Health Organization (WHO) reported penicillin-resistant S. pneumoniae as an important resistant combination, and this bacterial resistance causing a significant public health problem worldwide and reported it as the important bacterial etiology of the hospital and/or community-acquired infections.