The expression of epstein-barr virus in breast cancer in relation to age
-Background: Breast cancer is the most common malignancy affecting females worldwide. The association of Epstein-Barr virus (EBV) with this cancer is a longstanding interest to this field. Aim : to investigate the presence of EBV in breast tumor tissue in relation to age. Patients and Methods : Para...
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Veröffentlicht in: | Al-Kindy College medical journal 2011-06, Vol.7 (1), p.79-81 |
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Sprache: | eng |
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Zusammenfassung: | -Background: Breast cancer is the most common malignancy affecting females worldwide. The association of Epstein-Barr virus (EBV) with this cancer is a longstanding interest to this field.
Aim : to investigate the presence of EBV in breast tumor tissue in relation to age.
Patients and Methods : Paraffin-embedded tissue blocks from 45 female patients with breast tumors (ranged in age from 28 to 85 years) were retrieved. The cases were grouped into two categories : group (A) : included 30 cases with breast carcinoma and group (B) : included 15 cases with benign breast diseases as a control group .The expression of EBV protein was examined
Immunohistochemically.
Results : Twelve (40 %) of the 30 breast cancer cases (group A) were reported as positive for EBV expression and significantly higher in patients less than 40 years age (P= 0.026)
Conclusion : the results of the current study might refer to the significance of EBV expression in breast tissue of young patients with breast cancer. |
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ISSN: | 1810-9543 2521-4365 |