Geriatric Nutrition Risk Index: Prognostic factor related to inflammation in elderly patients with cancer cachexia

Background Systemic inflammation and cachexia are associated with adverse clinical outcomes in elderly patients with cancer. The Geriatric Nutritional Risk Index (GNRI) is a simple and useful tool to assess these conditions, but its predictive ability for elderly patients with cancer cachexia (EPCC)...

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Veröffentlicht in:	Journal of cachexia, sarcopenia and muscle sarcopenia and muscle, 2021-12, Vol.12 (6), p.1969-1982
Hauptverfasser:	Ruan, Guo‐Tian, Zhang, Qi, Zhang, Xi, Tang, Meng, Song, Meng‐Meng, Zhang, Xiao‐Wei, Li, Xiang‐Rui, Zhang, Kang‐Ping, Ge, Yi‐Zhong, Yang, Ming, Li, Qin‐Qin, Chen, Yong‐Bing, Yu, Kai‐Ying, Cong, Ming‐Hua, Li, Wei, Wang, Kun‐Hua, Shi, Han‐Ping
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aging Body mass index Cachexia - diagnosis Cachexia - epidemiology Cachexia - etiology Cancer cachexia Cardiovascular disease Cohort Studies Colorectal cancer Elderly Gastric cancer Geriatrics GNRI Hospitals Humans Immune system Inflammation Informed consent Laboratories Lung cancer Male Malnutrition Medical diagnosis Medical prognosis Musculoskeletal system Nutrition Nutrition Assessment Nutritional status Older people Original Overall survival Patients Prognosis Retrospective Studies Statistical analysis Stomach Neoplasms Systemic inflammation Womens health
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Zusammenfassung:	Background Systemic inflammation and cachexia are associated with adverse clinical outcomes in elderly patients with cancer. The Geriatric Nutritional Risk Index (GNRI) is a simple and useful tool to assess these conditions, but its predictive ability for elderly patients with cancer cachexia (EPCC) is unknown. Methods This multicentre cohort study included 746 EPCC with an average age of 72.00 ± 5.24 years, of whom 489 (65.5%) were male. The patients were divided into two groups (high GNRI group ≥91.959 vs. low GNRI group
ISSN:	2190-5991 2190-6009
DOI:	10.1002/jcsm.12800