Common causes and characteristics of adverse drug reactions in older adults: a retrospective study

Aging populations are often accompanied by comorbidity and polypharmacy, leading to increases in adverse drug reactions (ADRs). We sought to evaluate the causes and characteristics of ADRs in older Korean adults (≥65 years) in comparison to younger individuals (

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Veröffentlicht in:	BMC pharmacology & toxicology 2020-12, Vol.21 (1), p.87-9, Article 87
Hauptverfasser:	Woo, Seong-Dae, Yoon, Jiwon, Doo, Go-Eun, Park, Youjin, Lee, Youngsoo, Lee, So-Hee, Lee, Young-Hee, Ye, Young-Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Adverse drug reaction Adverse Drug Reaction Reporting Systems Age Age Factors Aged Aged, 80 and over Aging Analgesics Analysis Anaphylaxis Anti-inflammatory agents Causality Comorbidity Complications and side effects Confidence intervals Contrast media Data models Databases, Factual Demographics Drug hypersensitivity Drug-Related Side Effects and Adverse Reactions - diagnosis Drug-Related Side Effects and Adverse Reactions - epidemiology Drugs Female Fentanyl Hospitalization Hospitals Humans Inflammation Male Middle Aged Nonsteroidal anti-inflammatory drugs Older people Patients Pharmacovigilance Physicians Polypharmacy Population studies Prescription drugs Product safety Republic of Korea - epidemiology Retrospective Studies Side effects Terminology Tramadol
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Beschreibung
Zusammenfassung:	Aging populations are often accompanied by comorbidity and polypharmacy, leading to increases in adverse drug reactions (ADRs). We sought to evaluate the causes and characteristics of ADRs in older Korean adults (≥65 years) in comparison to younger individuals (
ISSN:	2050-6511 2050-6511
DOI:	10.1186/s40360-020-00464-9