A Study on the Diurnal Variation of Ventricular Repolarization Parameters in Patients with Obstructive Sleep Apnea

BackgroundObstructive sleep apnea hypopnea syndrome (OSAHS) is a common sleep breathing disorder. More and more studies have shown that OSAHS has a significant correlation with cardiovascular disease. It is an independent risk factor for arrhythmia, hypertension, coronary heart disease and other cardiovascular diseases, but the specific mechanism is still not completely clear. Relevant evidence indicates that ventricular repolarization parameters such as Tp-e interval, QT interval and Tp-e/QT ratio may be related to arrhythmia and even sudden cardiac death. However, up to now, there are relatively few studies on OSAHS-related arrhythmias and changes in cardiac electrical parameters.ObjectiveTo study the diurnal variation of ventricular repolarization parameters in patients with obstructive sleep apnea.MethodA total of 159 OSAHS patients who met the inclusion criteria and received polysomnography monitoring in the First Affiliated Hospital of Zhengzhou University from June 2020 to July 2021 were selected as th