Probing the chemical constituents of Cassia javanica and its in vitro analyses as a potent drug
The phytochemical screening of the crude methanolic stem extracts of plant showed the presence of different classes of organic compounds like alkaloids, tannins, flavonoids, saponins, phlobatanins, steroids, anthraquinone and cardiac glycoside. The starching frequencies of these functional groups we...
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Veröffentlicht in: | Royal Society open science 2022, Vol.9 (1), p.211626-211626 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The phytochemical screening of the crude methanolic stem extracts of
plant showed the presence of different classes of organic compounds like alkaloids, tannins, flavonoids, saponins, phlobatanins, steroids, anthraquinone and cardiac glycoside. The starching frequencies of these functional groups were determined from FT-IR spectroscopic data. The crude and their fractions were examined for antibacterial potential against
and
. The antibacterial assay showed maximum zone of inhibition for ethyl acetate fraction, i.e. 20 mm against
and 18 mm against
in the comparison with Levofloxacin used as standard (40 mm). Meanwhile for methanolic crude extract, the inhibition zone was recorded 14 mm against
and 22 mm against
. The minimum inhibitory concentrations and minimum bactericidal concentrations were recorded as 187.5 µg ml
against
and 93.75 µg ml
against
The scavenging free radical assay was noted as 69.61% at the concentration of 100 ppm. |
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ISSN: | 2054-5703 2054-5703 |
DOI: | 10.1098/rsos.211626 |