Detection of Norovirus Variant GII.4 Hong Kong in Asia and Europe, 2017-2019

We report a new norovirus GII.4 variant, GII.4 Hong Kong, with low-level circulation in 4 Eurasia countries since mid-2017. Amino acid substitutions in key residues on the virus capsid associated with the emergence of pandemic noroviruses suggest that GII.4 Hong Kong has the potential to become the...

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Veröffentlicht in:	Emerging infectious diseases 2021-01, Vol.27 (1), p.289-293
Hauptverfasser:	Chan, Martin Chi-Wai, Roy, Sunando, Bonifacio, Joseph, Zhang, Lin-Yao, Chhabra, Preeti, Chan, Jenny C M, Celma, Cristina, Igoy, Mary Ann, Lau, Sin-Leung, Mohammad, Kirran N, Vinjé, Jan, Vennema, Harry, Breuer, Judith, Koopmans, Marion, de Graaf, Miranda
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acids Caliciviridae Infections - epidemiology Data analysis Detection of Norovirus Variant GII.4 Hong Kong in Asia and Europe, 2017−2019 Dispatch Distribution Epidemics Europe - epidemiology Evolution Gastroenteritis Gastroenteritis - epidemiology Genomes Genotype Health surveillance Hong Kong - epidemiology Humans Identification and classification Infections new variant Norovirus Norovirus - genetics norovirus GII.4 Pandemics Phylogenetics Phylogeny Proteins Public health RNA polymerase surveillance Vaccines Varieties Viral infections Viruses
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Zusammenfassung:	We report a new norovirus GII.4 variant, GII.4 Hong Kong, with low-level circulation in 4 Eurasia countries since mid-2017. Amino acid substitutions in key residues on the virus capsid associated with the emergence of pandemic noroviruses suggest that GII.4 Hong Kong has the potential to become the next pandemic variant.
ISSN:	1080-6040 1080-6059
DOI:	10.3201/eid2701.203351