Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance

Keywords: Long non-coding RNA, Cancer resistance, DNA damage repair, ATR

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Bibliographische Detailangaben
Veröffentlicht in:	Molecular cancer 2021-07, Vol.20 (1), p.94-94, Article 94
Hauptverfasser:	Liu, Lei, Chen, Yuanyuan, Huang, Yijuan, Cao, Kun, Liu, Tingting, Shen, Hui, Cui, Jianguo, Li, Bailong, Cai, Jianming, Gao, Fu, Yang, Yanyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Animals Antibodies Apoptosis Ataxia Telangiectasia Mutated Proteins - metabolism ATR ATR protein B cells Biotechnology Camptothecin Cancer Cancer resistance Cancer therapies Cell cycle Deoxyribonucleic acid DNA DNA damage DNA damage repair DNA repair Drug Resistance, Neoplasm - genetics Etoposide Experiments Genetic aspects Health aspects Heterografts Histones Homologous recombination Humans Ionizing radiation Kinases Letter to the Editor Long non-coding RNA Lung cancer Lung carcinoma Lung Neoplasms - genetics Lung Neoplasms - metabolism Mice Non-coding RNA Phosphorylation Protein binding Protein Stability Proteins Radiation therapy Recombinational DNA Repair - genetics RNA RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism Squamous cell carcinoma Tumors
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Beschreibung
Zusammenfassung:	Keywords: Long non-coding RNA, Cancer resistance, DNA damage repair, ATR
ISSN:	1476-4598 1476-4598
DOI:	10.1186/s12943-021-01382-y