Associations of polymetabolic risk of high maternal pre-pregnancy body mass index with pregnancy complications, birth outcomes, and early childhood neurodevelopment: findings from two pregnancy cohorts

Associations of polymetabolic risk of high maternal pre-pregnancy body mass index with pregnancy complications, birth outcomes, and early childhood neurodevelopment: findings from two pregnancy cohorts

A substantial proportion of maternal pregnancy complications, adverse birth outcomes and neurodevelopmental delay in children may be attributable to high maternal pre-pregnancy Body Mass Index (BMI). However, BMI alone is insufficient for the identification of all at-risk mothers and children as man...

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Veröffentlicht in:BMC Pregnancy and Childbirth 2024-01, Vol.24 (1), p.78-16, Article 78
Hauptverfasser: Girchenko, Polina, Lahti-Pulkkinen, Marius, Hämäläinen, Esa, Laivuori, Hannele, Villa, Pia M, Kajantie, Eero, Räikkönen, Katri
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Birth outcomes
Birth weight
BMI-defined metabolome
Body Mass Index
Care and treatment
Cesarean Section
Child development
Child, Preschool
Childhood
Childhood neurodevelopment
Children & youth
Cholesterol
Diabetes, Gestational
Diagnosis
Diseases
Female
Gestational age
Health aspects
High BMI-related polymetabolic risk score
Humans
Hypertension
Hypertension, Pregnancy-Induced
Infant, Newborn
Infants (Newborn)
Metabolism
Metabolites
Mothers
Obesity
Obesity, Maternal
Physiological aspects
Pre-Eclampsia
Pre-pregnancy BMI
Preeclampsia
Pregnancy
Pregnancy complications
Pregnancy, Complications of
Pregnant women
Premature birth
Premature Birth - epidemiology
Premature Birth - etiology
Psychological aspects
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Zusammenfassung:A substantial proportion of maternal pregnancy complications, adverse birth outcomes and neurodevelopmental delay in children may be attributable to high maternal pre-pregnancy Body Mass Index (BMI). However, BMI alone is insufficient for the identification of all at-risk mothers and children as many women with non-obesity(
ISSN:1471-2393
1471-2393
DOI:10.1186/s12884-024-06274-9