Immunological Features of Pediatric Interstitial Pneumonia Due to Mycoplasma pneumoniae

Inflammatory response, oxidative stress, and immunologic mechanism are involved in the pathogenesis of pneumonia (MPP). However, the role of immune system of pediatric interstitial pneumonia due to infections remains poorly understood. The aim of this study was to analyze the immunologic features of pediatric interstitial pneumonia due to . A retrospective study was conducted on a primary cohort of children with MPP. Propensity score analysis was performed to match interstitial pneumonia and pulmonary consolidation children. The clinical characteristics strongly associated with the development of interstitial pneumonia were boys, age >5 years, wheezing history, hydrothorax free, lymphocytes (>3.0 × 10 /L), CD19 (>0.9 × 10 /L), CD3 (>2.5 × 10 /L), CD4 (>1.5 × 10 /L), CD8 (>0.9 × 10 /L), interleukin-6 (IL-6,