The effect of glucomannan supplementation on lipid profile in adults: a GRADE-assessed systematic review and meta-analysis

Glucomannan has been studied for various health benefits, but its effects on lipid profile in adults are not well understood. This meta-analysis aims to evaluate the impact of glucomannan supplementation on serum/plasma levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	BMC cardiovascular disorders 2024-10, Vol.24 (1), p.545-15, Article 545
Hauptverfasser:	Musazadeh, Vali, Rostami, Rogheye Yaraee, Moridpour, Amir Hossein, Hosseini, Zahra Bokaii, Nikpayam, Omid, Falahatzadeh, Maryam, Faghfouri, Amir Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biomarkers - blood Blood cholesterol Body mass index Cardiovascular diseases Cholesterol Clinical trials Control Diet therapy Dietary Supplements Dyslipidemia Dyslipidemias Dyslipidemias - blood Dyslipidemias - diagnosis Dyslipidemias - drug therapy Female Glucomannan Grey literature Health aspects High density lipoprotein Humans Lipid profile Lipids Lipids - blood Lipoprotein Low density lipoprotein Male Mannans - administration & dosage Mannans - blood Meta-analysis Metabolic disorders Middle Aged Physiological aspects Plasma levels Prevention Randomized Controlled Trials as Topic Risk factors Statistical analysis Supplements Systematic Review Treatment Outcome Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Glucomannan has been studied for various health benefits, but its effects on lipid profile in adults are not well understood. This meta-analysis aims to evaluate the impact of glucomannan supplementation on serum/plasma levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), Apo B1, Apo A1, APO-B/ A1 ratio, and LDL-C/ HDL-C in adults. A comprehensive search was conducted across Scopus, PubMed, Embase, and Web of Science from inception to June 2024 to identify randomized controlled trials (RCTs) assessing glucomannan supplementation on lipid profile in adults. Data were extracted and analyzed using random effects model to determine the standardized mean differences (SMDs) and 95% confidence intervals (CIs) for each biomarker. Glucomannan supplementation significantly decreased TC (SMD: -3.299; 95% CI: -4.955, -1.664, P
ISSN:	1471-2261 1471-2261
DOI:	10.1186/s12872-024-04223-0